|GRANT||FUNDING AGENCY||PRINCIPAL INVESTIGATOR|
|Pharmacochemical Studies of Opioid Narcotics
(active through August 2004)
|Molecular Modeling, Design, & Evaluation of BDZ Ligands
(completed in January 2003)
|NIH-NIDA||Timothy M. DeLorey|
Treatment of various human physiological disorders remains a major challenge in the biomedical field. Numerous ailments lack effective therapies, while others with accepted therapies remain a challenge due to the side effects associated with the specific treatment. A major cornerstone of any therapeutic intervention is the use of pharmacological agents. Our goal is to design therapeutic strategies using drugs that exhibit a more precise effect while minimizing detrimental side effects. We approach this goal using a unique combination of experimental and computational methodologies.
We are currently applying this strategy to:
To read about the interaction between drugs and
G Protein Coupled Receptors (GPCRs), click here.